Viral detection in hydrops fetalis, spontaneous abortion, and unexplained fetal death in utero

Mesalazine as a cause of fetal anemia and hydrops fetalis

RATIONALE Mesalazine and its prodrug sulfasalazine are both used for inflammatory bowel disease. Sulfasalazine has been associated with hematological side-effects such as aplastic and hemolytic anemia in patients, but also in fetuses after intrauterine exposure. To our knowledge, we describe the first case of a fetus with severe anemia, and subsequent hydrops, where this drug was found at conce...

[Non-immunologic hydrops fetalis].

Non-immune hydrops fetalis

Aetiology of hydrops fetalis.

These 2 cases provide additional examples of HUS occurring in sibs after a long interval. The family resided in New York City, which is not considered as an endemic area for HUS, and the clinical course of the disease in both infants was almost identical, culminating in early death. The aetiology of HUS may indeed be multiple, and the genetic basis for a significant proportion of cases does not...

Non immune hydrops fetalis.

With the decline in the frequency of rhesus isoimmunisation, hydrops fetalis secondary to other factors is becoming increasingly recognised. We describe a case in association with chorioangioma of the placenta. The causes of non immune hydrops are reviewed and the problems of management discussed.